Monday, December 30, 2019

A Vindication Of The Rights Of Women - 1560 Words

America has roots deeply ingrained in sexism; a great illustration is that fact that it was not until 1920 that women were granted suffrage. To put that in perspective, in the United States, women have been voting for less than 100 years. With Mary Wollstonecraft’s book, A Vindication of the Rights of Woman: with Strictures on Political and Moral Subjects being published in 1792 and launching 19th century feminism and the fight for women’s rights going since then, many would think that equality would be here by now.Unfortunately, it is not. However, women did receive suffrage in the United States on August 26, 1920. The road to getting there, however, was a long and rough one. In response to Charles Maurice de Talleyrand-Pà ©rigord s 1791 report to the French National Assembly that had stated that the only education a woman should receive is one the domestic nature, Wollstonecraft wrote A Vindication of the Rights of Woman. In this piece she talks of women in a seemingly â€Å"abstract† way as she does not apply her reasonings to only British women or women of the 18th century. She says that women should also be educated so they can have opportunities to contribute in society. She tells of the fact that society will collapse without educated women as they have influence over young children as mothers. Wollstonecraft also writes, taught from their infancy that beauty is woman s sceptre, the mind shapes itself to the body, and, roaming round its gilt cage, only seeks to adornShow MoreRelatedThe Vindication Of The Rights Of Women1369 Words   |  6 Pagesaddresses the work of Mary Wollstonecraft, The Vindication of the Rights of Women. To investigate this, I will first summarize her work and someone else s interpretation of it, then analyze the author, voice, message and significance, and finally analyze the two works to answer the question, What are the current ideas about your philosopher? How have their ideas influenced us today?. My first souce will be the primary source of the Vindication, and my secondary source will be Matilde MartinRead MoreA Vindication Of The Rights Of Women981 Words   |  4 Pagessentimental romances, and by the misogynistic images of women perpetuated in, for instance, Milton’s Paradise Lost† (Gilbert Gubar 41). In the second chapter of A Vindication of the Rights of Women, Wollstonecraft discusses her frustration when it comes to women’s ignorance. She does not understand why men are frustrated when it comes to the ignorance of women. Women during this time were not raised to be observant or mindful (Wollstonecraft 43). They are taught how to needlepoint or play the pianoRead MoreA Vindication Of The Rights Of Women921 Words   |  4 Pagesthat another problem has risen. Mary Wollstonecraft, a social and political activist for women’s rights, addressed a letter to a former bishop to present a case of equality in relation to France’s government and societal restrictions imposed on women. As a sequel to her previous piece, â€Å"A Vindication of The rights of Women†, Wollstonecraft took the liberty to propose multiple reasons as to why women’s rights are essential to the well-being of not only men, but also as necessary for society to functionRead MoreA Vindication Of The Rights Of Women1350 Words   |  6 PagesWomen in London played a vital role in setting the foundation for the future of women’s rights in Western Civilization. Not only were barriers broken within London, but they became very influential to the future of the liberation movement for women. Interestingly enough, they are believed to be one of the erectors of modern day feminism. Mary Wollstonecraft was an ebullient advocate for women’s rights during the Enlightenment. During this time period, Wollstonecraft taught a new philosophy regardingRead More`` A Vindication Of The Rights Of Women ``908 Words   |  4 PagesWhere would we be without individuals like John Locke, Isaac Newton, Benjamin Franklin, and Thomas Jefferson? Without them, certain elements and ways of thinking that we know today, such as natural rights, would not be evident in society. These individuals were part of a group of philosophers, scientists, and writers who urged for the upbringing of new concepts based on logic. This period was known as the Age of Enlightenment which took place throughout the 18th century in Europe. During this timeRead MoreA Vindication Of The Rights Of Women1924 Words   |  8 Pages In the 18th century, women had virtually no rights. They were not allowed to work or vote. Instead, women were subjected to the household: cooking, cleaning, and taking care of the children. Consequently, women who were tired of being subjugated by society created the feminist movement. Feminism is the fight for the equality of the sexes. Throughout this fight, there had been several texts written to illuminate the many struggles of women and the ways to resolve these struggles. Among the firstRead MoreEssay on The Vindication of Rights of Women1373 Words   |  6 PagesIn Mary Wollstonecraft’s essay â€Å"A Vindication of the Rights of Women† she constantly compares men and women. Her comparisons range from their physical nature to their intelligence, and even down to the education that each sex receives. Wollstonecraft states, â€Å"In the government of the physical world it is observable that the female in point of strength is, in general, inferior to the male.†(line 1.35-37) to show that women are inferior to men in physicality, and a number of areasRead MoreA Vindication Of The Rights Of Women By Mary Wollstonecraft1192 Words   |  5 Pagesplaces upon her. Inspired by the writing, A Declaration of the Rights of Woman and the Female Citizen, which demanded equal rights for both men and women, Wollstonecraft published her book, A Vindication of the Rights of Women, which called for both men and women to realize their roles concerning inequality. The book also allowed for Wollstonecraft to express her ideas and methods for the improvement of equality between the sexes. Vindication went on to print many times throughout the 18th and 19th centuriesRead MoreWomen And Material Things : The Vindication Of The Rights Of Women997 Words   |  4 PagesAssignment 2 December 6, 2014 Women and Material things The Vindication of the Rights of Woman by Mary Wollstonecraft is a compelling arguement that argues for equality for women in society. The Weaver’s Complaint Against the Callico Madams explains outcome of women’s with equal rights would do to society. Sanshiro written by Natsume Soski, focuses the details and experience of his life spent at a prestigious Tokyo University. Three of these readings relate to women and material things because theyRead More Wollstonecrafts A Vindication of the Rights of Women Essay1291 Words   |  6 Pagesher worth. During the Enlightenment, some women began to question this norm and to voice their unhappiness. The Enlightenment period was an intellectual movement that sought to reform society and advance knowledge (â€Å"Age of Enlightenment†). Even with all of the Enlightenment’s great advancements, women still did not possess many rights. Women continued to be â€Å"oppressed and kept to the private sphere,† separa ted from men (â€Å"Women in the Enlightenment†). Few women challenged these social norms, but a few

Sunday, December 22, 2019

A Study Of Ethics By Immanuel Kant And John Stuart Mill

The study of ethics is the study of right and wrong in human behavior. The R.v Lavallee case revolves around ethics. The court released Lavallee as innocent on the basis that she is medically ill with Battered Woman Syndrome (BWS). The two most renowned ethicists, Immanuel Kant and John Stuart Mill would view this case differently. Kantianism is associated solely with Immanuel Kant. In comparison, John Stuart Mill, an opponent of Immanuel Kant’s ideas, uses a utilitarian approach. This essay will briefly give an overview of the case and the BWS. Then, it will show how both theories view the case. Overall, this paper argues that Mill’s theory is a better theory that supports the verdict. R.v Lavallee: Brief Overview The case is centered on Angelique Lyn Lavallee. Lavallee was in an abusive relationship with her husband, Kevin Rust. Lavallee was in an abusive, emotional, and physical relationship with Rust for nearly four years. Lavallee often visited the hospital for injuries and she lied to the hospital staff when questioned about her injuries. On August 31st, the couple hosted a party at their home and got into an argument. Rust threatened Lavallee’s life and in fear Lavallee shot Rust as he exited the room, killing Rust immediately. During the trial, many witnesses came and provided testimony that Lavallee was being abused by Rust severely. Dr. Shane, a medical psychiatrist diagnosed Lavallee and concluded that she has symptoms of BWS. In the end, the court concludedShow MoreRelatedKant And Mill On Animal Ethics Essay1365 Words   |  6 PagesIn this essay I will begin by explaining the overall views of Immanuel Kant and John Stuart Mill, then compare and contrast the ideas and philos ophies of Kant and Mill on Animal Ethics. I believe that Kant, the deontologist, will not care as much about the duty/responsibility between humans and animals as Mill, the utilitarian, who will see the extreme importance of animal ethics. After studying and explaining the views and teachings of these two philosophers I will see if my thesis was correct,Read More Immanuel Kants Ethics Of Pure Duty and John Stuart Mills Utilitarian Ethics Of Justice2753 Words   |  12 PagesImmanuel Kants The Grounding For The Metaphysics of Morals and John Stuart Mills Utilitarianism Immanuel Kant and John Stuart Mill are philosophers who addressed the issues of morality in terms of how moral traditions are formed. Immanuel Kant has presented one viewpoint in The Grounding For The Metaphysics of Morals that is founded on his belief that the worth of man is inherent in his ability to reason. John Stuart Mill holds another opinion as presented in the book, Utilitarianism thatRead MoreJohn Stuart Mill And Immanuel Kant1786 Words   |  8 PagesJohn Stuart Mill and Immanuel Kant. They both had very different views when it came to the ethics of philosophy. They also though had some of the same views as each other. Both were concerned with the moral qualities of actions and choices of a person, but neither of them was much interested in about what makes a good person. They also different views and some of the same views when it came to lying. One thought it should never be done. The other thought it should be used as a last resort. FirstRead MoreMoral Judgements Are Morally Wrong?2025 Words   |  9 PagesEthics is an area of philosophy that deals with what is morally right and what is morally wrong behavior. Inside of ethics, there are two major views of thinking when making choices about different principles. Deontology is the idea that choices should be made based on obeying moral norms. Moral judgements are contained in an act alone. A deontologist would decide on the moral worth of an action based on the intention of the action. Immanuel Kant, an eighteenth century German philosopher, is consideredRead MoreMill and Kants Efforts to Solve an Ethical Dilemma822 Words   |  4 Pagesthe moral theories of John Stuart Mill and Immanuel Kant is solving an ethical dilemma. John Stuart Mill opens his utilitarian postulation by asserting that ethical statements cannot be subjected to scientific or mathematical provability (West 23). Mill’s utilitarianism is the moral standpoint that views actions as right or wrong in proportion to how they advance happiness or pleasure (Bailey 23). By maximizing utility, Mill implies increasing happiness (West 57). Mill urges moral actors toRead MoreThe Value Of A Life1454 Words   |  6 Pages â€Å"What is the value of a life?† This is a question that has plagued humanity for thousands of years. There doesn’t seem to be a definitive answer even after years of long thought and study. The main reason revolves around the idea of determining which qualities are needed in order to measure the â€Å"value of a life†. For example, is a person’s net worth the most important quality that needs to be considered or should other things be considered such as how many people was this person able to make happyRead MorePhilosophical Analysis of Aristotle883 Words   |  4 PagesAristotle Many theorists consider Aristotle to be the first person to use the term â€Å"ethics† in naming the field of study that had already been subject to develop by his predecessors Socrates and Plato. Philosophical ethics attempts in offering the rational response to the questions regarding how the human beings live. Aristotle used to be regarding politics and ethics as two related but very separate field of study because ethics examines the good concerning an individual, while politics is about examiningRead MoreKant: Moral Theories1002 Words   |  5 Pagesto Timmons, the field of philosophy is not complete without the mention of Kant whose contributions were major (205). This, he adds, was influenced by his originality, subtle approach and the difficulty of his works. Timmons cites that moral requirements are a requirement of reason, which is the ideology of Kant’s Moral theory; hence, immoral act is an act against reason. Consequently, speaking on the terminologies of Kant we visualize moral requirements as Categorical Imperatives (CI) grounded onRead MoreJohn Stuart Mill s Philosophy On The Morality And Ethical Nature Of The Subject1507 Words   |  7 Pageslives through use of their organs, a utilitarian like John Stuart Mill would argue that cloning is morally acceptable due to the maximized utility. Kantian Immanuel Kant is considered the central figure of modern philosophy. Kant sought to refute thinkers like David Hume and John Stuart Mill. Kantian Philosophy is considered deontological in that it holds that an action is right in and of itself without appeal to consequences. According to Kant, a faculty of the human mind called practical reasonRead MoreThe Philosohpy of Immanuel Kant1191 Words   |  5 PagesImmanuel Kant is referred to as the â€Å"father† of deontological ethics, which is also colloquially referred to as Kantianism, which provides a sophisticated explication of deontology. His philosophy embodies capitulating to one’s maxim, which he beliefs that to be good, however, only if one’s motives are unconditional and irrespective to external reason. The maxim is referred to as the individual’s intrinsic duty or obligation to one’s self or to others, which if applicable to everyone than it is congenial

Saturday, December 14, 2019

In what circumstances is it appropriate to decentralise decision making Free Essays

Decentralisation of decision making is the process of involving different people in an organization in making key changes whether these changes are policy based or otherwise, different levels of management are involved and their expertise and opinion is sought before any changes are enacted. There are 2 key decisions making methods in an organisation, namely centralized and decentralized, In the latter, only the top management is involved in making key changes and decisions which affect the whole organization. This system is advantageous in that, it is faster, reliable and less tasking. We will write a custom essay sample on In what circumstances is it appropriate to decentralise decision making? or any similar topic only for you Order Now While it is still used in majority of organizaions, most organizations are shifting to the decentralised method and therefore are involving different levels of management in the decision making process. This system is ideal in a number of situations as explained below. Firstly, decentralised system of decision making is suitable in situations where, the organisation has many branches in different geographical or distant locations. This is usually necessitated by the fact that, there arise emergency situations whereby key and quick decisions have to be arrived at and therefore contacting the central decision making authority within a short period of time is out of question question. Secondly, decentralised decision making process is preferred when an organisation is experiencing major staff turnover and their fore lack of key management staff through sackings or retires or any other natural attrition method warrants decisions to be made irregardless. Thirdly, decentralised decision making process is ideal whereby, key decisions are being made at departmental levels such as in production department. Empowering departmental heads to make key decisions perhaps pertaining to the purchasing of crucial ingredients as well as other technical areas may require a decentralised decision making model. PAGE 2: Organisational culture can present difficulties for management initiated change programmes? Discuss Organisational culture refers to the employee – employer relations which shape how the two parties interact and intermingle at the work place. Also, organisational culture can be shaped by, employee backgrounds, external factors as well as the level of support accorded to the employees by the organization staff. Usually there are two common types of organisational cultures namely, positive and negative culture. The first one affects management initiated programmes in that, employees experiencing this kind of culture are more likely to accept any changes in the organisation as usually there is a good blood between the two parties which therefore translates into a strong trust, and mutual understanding. In such an environment, any changes coming from the management whether good or bad are welcomed without any queries and are looked at as being beneficial to the employees. This in turn leads to failure of pragrammes initiated by the management in that, as long as the staff who are tasked with project implementing do not question anything in terms of abnormalities and even if there are clearly missing facts, this is never realized until it is too late therefore causing programme failure. On the other hand an organization culture which is negative leads to customers shunning away so that, any well meant programmes will be fail to take off since, negative publicity which the employees can advance in the process of interacting with the different stake holders also does have a bearing on the outcome of the projects. Lastly, organizational culture determines output in workers in that, a negative attitude amongst employees is more likely to lead to low output in that, it is highly correlated with low morale and therefore productivity. PAGE 3: Discuss why managerial authority is so important to our understanding of organisations and how this power has to be legitimised not just by individual workers but by the organisations culture. Failure to appreciate managerial authority stems form a negative culture which in stead of pestering a mutual understanding between workers and employers causes tensions and misunderstandings in an organization. Usually, for the organisation to meet its goals and objectives the management has to execute its duties well just as stipulated in functions of management. This involves carrying out duties and responsibilities which must be commensurate with the corresponding authority. In situations whereby managers are allocated duties and responsibilities without proper and clear cut, authority to accompany it, the management becomes ineffective and this contributes to failure of many organizations. Therefore, there is a need for decision makers while allocating managers duties to weigh the responsibilities and duties assigned to employees versus the authority and power required to execute the roles and responsibilities effectively. To achieve the above, management should work towards having and inculcating in the organization, the right culture. This can be achieved (if it is lacking), through the launching of strategic plans which could incorporate vision and mission statements, core values of the organization as well as the social responsibility statement of the organization. All the above are necessary in ensuring that, the organization functions in the right environment whereby the needs of all members in the organization are taken care of and employees feel free and as a part of the organization. This in turn result into a culture of unity and strength. How to cite In what circumstances is it appropriate to decentralise decision making?, Papers

Friday, December 6, 2019

Nursing - Professionalism free essay sample

This paper discusses the difficulties faced by nursing in being defined as a profession. This work analyzes the term professionalism and describes the struggle Nursing faces in try to be defined as a profession. It presents a history of Nursing from the days of Florence Nightingale and details the changes that have occurred in the field in modern day which justifies its fight for recognition. From the paper: Stopper 98) Ever since the publication of Florence Nightingale?s classic nursing textbook, Notes on Nursing in 1859, nursing has been preoccupied with its image and status, not only within the health care environment, but also within society at large. This long journey through the slow process of professionalization is not quite over, and the recent increase in the level of debate could not have been better timed, coming as it does at a time when nursing faces the important challenges involved in adjusting to the emerging new order of health care delivery. We will write a custom essay sample on Nursing Professionalism or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page

Friday, November 29, 2019

Universe Existence Essays - Black Holes, , Term Papers

Universe Existence The oldest profession in the world is not what would be commonly accepted in society. Before a woman had a chance to sell her body, people looked up at the stars and wondered what they were. They made figures out of the shapes they made. As we advanced through scientific research many other doors opened that allowed us to see what it was the earth is existing in. Our constant need to explain what is happening comes from our want to control. Knowledge is power, and nothing is more unexplained that the universe. Time is interlocked and must be understood if we want to accomplish a deep knowledge of the cosmos. Commonly it was thought that there was no such knowledge. The author Stephen Hawking had shown many otherwise. His books give a deep history and knowledge of how the universe exists. He also explains many others aspects of the cosmos and puts his works in an understandable writing style. He puts the largest accent on his studies of black holes. These are fascinating happening and the way to understanding the universe and several others can be found through the study of black holes. There are several features of black holes that makes them incredibly fascinating. The first one would be the common misconception of how noting can escape a black hole. This is true in most points. If nothing can escape them, how does one detect a black hole? Stephen Hawking discovered a fascinating aspect using anti-particle properties. He found that when matter is pulled into a black hole by gravity matter is constantly being pulled apart. This causes the anti-parties of matter to be throw away at incredible rates. This happens at consistent times. The large amount of gamma radiation let off by this is how Mr. Hawking now finds black holes. Another interesting concept of black holes is they are can be formed other ways than by the end of a star's life. Stephen Hawking and his associates found that any nuclear explosion can cause the birth of a black hole. Hawking stated that is all the "heavy water", a component used in nuclear weapons, was used to create a nuclear explosion a black hole the size of earth would be created. He also stated no one would be around to witness the creation. It would have been caused by the implosion of earth at a massive rate and the amount of energy produced by the nuclear explosion. This had me wondering. Stephen Hawking also stated that is a black how small enough not to disturb the orbit of earth existed close enough to earth that it's power could be harnessed to produce huge amounts of energy. This made me wonder if the same concept could be used, except with all the wastes materials on earth. I do not know the exact physics of it all, but from Mr. Hawking explanations it seemed like it might work. Black holes were also explained by Stephen Hawking as how they transcended time. Apparently the massive gravitational pull creates a rip in the space-time continuum. It is unknown what happens to matter when it is pulled into a black time wise. All matter will be ejected into space eventually as the black hole loses itself. The smaller a black hole, the more matter is ejected. It may be an odd happening, but because of the larger black holes are harder to detect than smaller black holes. Mr. Hawking stated of how if an astronaught gets pulled into a black hole the tidal forces would stretch him into a long piece of spaghetti like person. However, his life would not end in the black hole. Given enough time he would be eventually ejected into space as particles. All matter in a black hole will eventually be lost into space. The smaller a black hole is, the more matter is lost by the black hole. Stephen Hawking explained what is thought to have happened to a black hole when all its matter is lost. The hole in the space-time continuum would collapse and an explosion as massive as on of a supernova would happen. It would leave the tear in time. I wondered when the explosion would happen? Would it happen now, or ten to trillions of years from when it actually collapses. The tear in time where would it exist? Until an actual black hole is found close enough to us I suppose these questions will remain uninsured. Stephen Hawking explains many other aspects of

Monday, November 25, 2019

A New Life Essay Essay Example

A New Life Essay Essay Example A New Life Essay Essay A New Life Essay Essay A New Life Hopefully everyone can relate to a significant event in their life. Something that might have created a big deal of emotions, perhaps sad or happy. For example; forever bonding with a partner by legally marrying, or maybe the joy of knowing that after all those hard sleepless nights you’re being rewarded a lot more of those not by one, but two little twins, or maybe, â€Å"just maybe† you might have been one of those lucky lottery players that has the chance to spend the rest of your life spending. But not me. One significant moment that changed the course of my life was getting hired by Homestead Hospital. For an event to be significant it must have some kind of value to you. At that point of my life that moment had a tremendous value because it not only rescue me from this choppy glass of water in where I was drowning and even though there was not enough water to relieve my thirst I was drowning in it, but it also gave me an opportunity to pursue my goals. Something that I was starting to feel the sense of never being able to do. The reason was; I had just found out that I was going to be a Daddy at the age of 19 and if that was not enough I was handed the ultimate ultimatum, a letter of â€Å"termination†. Termination! From where? Well if I know your question then you must know the answer. From my job. A job that was second to school but after the wonderful news of being a daddy it was telling school to move back one spot. It all started after a few days with no sleep, after a few days of driving, calling and more importantly a lot of rejections. In no point in life I had felt so miserably impotent and what at first started as days turned to weeks in a hurry. I had started to lose it when I received a call from a young lady from Homestead Hospital. She said she worked with Human Resources and politely asked me if I was still interested in the position I had applied for. For a second I talked to myself, and for a second I felt offended. But

Thursday, November 21, 2019

Termination Essay Example | Topics and Well Written Essays - 750 words

Termination - Essay Example In such instances, it generally becomes necessary for the organization to consider terminating the employee. Termination should be considered as the most severe form of punishment that an organization can possibly impose on an employee and as such, it should be the most carefully considered form of disciplinary action. The experience of going through a job termination is considered to be traumatic for all of an organization’s employees. Of note is that the termination of employees at different levels or positions within the same organization varies considerably; Unlike the employees working in the lower level positions of the organizations, an organization’s executives and CEOs often do not have to worry about the probability of their positions being eventually eliminated. The main worry that individuals at this level often have is that of ensuring that they constantly try and please the organization’s board of directors because it is these boards that are tasked with the responsibility of firing and hiring of these executives. Most of the time, the board of directors only undertakes the rather drastic action of firing an executive or CEO due to a loss of confidence in the executive. This loss of confidence might be brought about by a number of factors that include a general decline in the level of productivity, the emergence of philosophical differences between the executive in question and the board of directors, economic reasons, or if there is a need to reorganize the organization. Of note however is that there are currently no formal termination appeal procedures for employees at this level (Mondy, 2013, p. 367). This group of employees is widely considered to be the most neglected and vulnerable in respect to employment termination. While an organization’s executives generally tend to have a considerable degree of clout that might aid in helping them to successfully

Wednesday, November 20, 2019

I need write a letter to my parents in brazil, and explain to them Essay

I need write a letter to my parents in brazil, and explain to them what homeland security is and what my future will be in my ne - Essay Example The United States Department of Homeland Security came into existence in 2002 as a consequence of the Homeland Security Act. The Federal Homeland Security is responsible for coordinating the activities of roughly 187 Federal agencies dealing with varied aspects of the US security. The job of the Homeland Security is to prevent terrorist attacks on the US soil and to minimize the damage inflicted by such attacks. A career in such an agency requires a lot of sincerity, dedication, skills and hard work. It is different from the other jobs in the sense that it demands perpetual alertness and a 24 hour commitment from its adherents. However, those who are willing to give their best and utmost, it do promises ample satisfaction and rewards. Besides, the very concept and idea of working to protect the fellow citizens is in itself a source of great pride and motivation. I do believe that I will do really great in this career. Yours lovingly, Name of the Student.

Monday, November 18, 2019

Liability of Law Enforcement Officers WK7 Term Paper

Liability of Law Enforcement Officers WK7 - Term Paper Example Thus, the robber turns on his car trying to escape a police officer and the penalty which he had to follow. Police officer could not stop him, and he took a gun and fired. In that particular case, which is called ROCHELLE BROSSEAU v. KENNETH J. HAUGEN, robber sued the performer of Law. Verdict was in favor of the police officer. Also, the mother of three children reported to police that her estranged husband took children, and that he has a restraining order because of the application of force. Mother called a police for several times and they were saying to calm down and wait for him to come back. After several hours mother went to the police station, claiming that her kids are still missing.Few momments later her husband, the reported one, came into a station and opened a fire with his machine gun.Officers shot him down.In the back of his truck they found a dead children bodies.The mother filed a lawsuit against the city, its police and three officers that she was talking to on the phone; however the judgment was in their favor, and all of the lawsuits were objected. Police officers have a tough job, even without thinking about potential lawsuits, which does not mean that the law can be put into their own hands and to interpret it how they want. Police is indicated that the law in their hands and no one recalls that it isn`t the Law who is working for them, but they are working for the Law. Basic laws, such as in the first case, the Fourth Amendment violation, they neither respect nor were punished for it. Every man has right to say and do what he wants, if that is not against the Law. Every man has a right to be punished for his wrong dids and to take charge on anyone who is violating his right to live or express himself, in any way. Everyone have a right to have a fair trial, even if the prosecutor is tramp and the

Saturday, November 16, 2019

Natural Product and Metabolomics

Natural Product and Metabolomics Mass Spectrometry is often become very useful comes into the final confirmation stage of a chemical structure. This is because by noting the fragmentation pattern and the total molecular mass of compound, researchers will be able to confirm the compound’s chemical formula, followed by confirming the chemical structure proposed based on previous instrumental analyses. Nowadays, Gas Chromatography and Liquid Chromatography are coupled with mass spectrometry in order for researchers to obtain the molecular mass right after the compounds are separated chromatographically. However, GC-MS are more often being used to study natural product compared to LC-MS because LC-MS doesn’t have its database constructed like GC-MS due to the extensive range of secondary metabolites and it is hardly reproducible. (Lee Yoon et al., 2013) Researchers can confirm the compound by matching the molecular mass obtained from GC-MS with the established database, while LC-MS users will have to refe r to the data provided by previous researchers on that particular field of study. There are a lot of journals regarding the studies of primary and secondary metabolites being published and a lot of researches will insert their sample for GC-MS experiment and then compared their compound’s fragmentation pattern and also molecular weight to the National Institute of Standards and Technology libraries, which will tells researchers the structure of their compounds, even if there are no exact matching, researches will at least have a rough idea on their structure. In the early 1990s, Solid-phase microextraction (SPME) was introduced to extract compounds from samples without the use of solvent; this method is later applied on samples before undergoing GC-MS process. This technique enables researchers to extract compounds from sample in a much simpler and cheaper way since it doesn’t include the use of solvent. SPME works by adsorbing compounds into its fibre coated absorbing phase from the sample, and then inserted into GC for desorption of compound into it and then separated. (Dagostino Sanz et al., 2014) This technique is so convenient that researchers can even carry it along when going into a jungle to adsorb compounds from plant of interest and bringing it back to the lab to undergo GC-MS experiment, much more convenient than plucking a big bunch of plants sample to the lab for solvent soaking. Samples can be injected into GC-MS through either split of splitless injection; split injection system will direct most of the samples out to the atmosphere and only allow approximately 1% of it to enter the column while splitless injection system allows most of the samples to enter the column. Split/splitless system are designed to give reproducible chromatographic retention times and also to keep the chromatographic requirements of column in place, to use split of splitless, it is depending on the sensitivity required. Though splitless system allows more sample to be injected in however, metabolomics researches are better be carried out with split system because metabolites are present in wide range concentrations and it allows researchers to analyze volatile compounds eluting near the solvent peak. (Cyril Jousse, 2009) Besides plant’s metabolites, GC-MS is also very useful for bio-metabolics, some of the bio-metabolics researches are for example Chrysoula Christou et al. did a research on analysis of organic acids in human urine in clinical settings in order to develop a method for organic acid profiling in human urine, this can be useful to detect metabolics or other health disorders. Their sample was being separated by gas column and undergo quadrupole mass spectrometer in the electron ionization (EI) mode and as a result chromatogram and mass spectra shown 11 organic acids separated and identified by conducting similarity search on NIST library (3). A research was carried out by Ioannis Papoutsis and the team of research. where GC-MS method was used to determine amisulpride in blood. Amisulpride is an antipsychotic drugs which is prescribed to psychiatric patients, overdosing can cause arrhythmia, bradycardia and hypotension. (4) SPME was first used by them to extract compounds from the b lood samples and then separated by using gas chromatography and finally detected by mass spectrometer, results show that GC-MS can be used to monitor amisulpride in the blood and this can be used in pharmacokinetic studies and also forensic investigation. Archeology GC-MS is also used in assisting archaeology studies; it is especially useful when comes to determining the chemical constituents of the sample. In one of the recent archaeology research, M. Mà ©nager, C. Azà ©mard and C. Vieillescazes studied the mummification balms from the mummy skulls with FTIR and GC-MS. Twelve mummified heads were collected, the balms on the heads were extracted with organic solvent and water before introduced to GC-MS. Molecular components were eluted by using helium, and injected with split system. Samples were eluted by using helium as carrier gas with the flow of 1mL.min-1 and oven temperature was set to: 50  °C for 2 min, 50–250  °C at 8  °C ·min−1, 250–350  °C at 3  °C ·min−1, and 350  °C during 20 min. 1 ÃŽ ¼L of each sample was injected with a splitting system and the injection temperature was set at 250  °C. Mass spectra were generated by electron ionization mode with electron ionization energy of 70 eV, an ionization time of 25,000 ÃŽ ¼s and a mass range of 40–650 m/z. (5) As a result, those mummification balms were found to contain mixtures such as oils, fats, beeswax, resins, proteins, polysaccharides and minerals, these compounds are confirmed again by matching mass spectra with NIST library. With the use of only FTIR without confirmation by GC-MS, researchers will only be able to know the functional group in it without confirming the compounds. Cosmetic In cosmetic industries, chemical compounds in every cosmetic must be carefully studied as it’s applied onto human’s skin and body, therefore any mistake made will cause allergy or irritation to end users. Synthetic husk has been widely applied in cosmetic industry due ti its long-lasting odor, however, it was found that two groups of synthetic musk can cause many health disorders. Many countries have also set up regulations on the amount of synthetic musk in order to protect end users, this has become another parameter in quality control of cosmetic products. In Beijing, China, Haifeng Dong and his team of researchers conducted a research on 7 synthetic musk in cream by using SPME and then GC-MS, cream is chosen as it is the most common form of cosmetic product. (6) Cosmetic creams contains moisturizing, nutritional agent and also many lipophilic compounds. Synthethic musks have low polarity and it is also one of lipophilic compounds, which cause synthethic musks can be hardly be separated out from other liphophilic compounds. Cream samples must undergo extra cleanup steps such as by matrix solid phase dispersion method (MSPD) in order minimizes the matrix effect. Since water and isopropanol was used to separate synthetic musks from lipophilic compounds, supported liquid extraction will need to be used in order absorb water and remove interferences to give better purification. Tandem MS was used in this research in order to improve the selectivity and decrease the detection limit. This research which deals with dream shows slightly different in the preparation method compared to other GC-MS research, however, overall concept is still similar.

Wednesday, November 13, 2019

FINANCIAL MANAGEMENT Essay -- essays research papers

What do you understand by the phrase â€Å"stakeholder analysis†? Attempt a stakeholder analysis of an organisation that you are closely associated with. Introduction Stakeholder analysis is important for successful implementation of projects and/or strategic activities within any organisation. It is used to analyse the stakeholders in order to understand them and classify them according to their power, influence and interest. Stakeholders are people who have an interest in a commercial entity including those within the organisation and outside. These include the boss, senior executives, customers, suppliers, government, your co-workers, the team and others. All these people are important in the implementation and success of strategy. The tool stakeholder analysis is used to: - †¢Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Identify people or groups and institutions that will influence your initiative †¢Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Anticipate the kind of influence, positive or negative, these groups will have on your initiative †¢Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Develop strategies to get the most effective support possible for your initiative and reduce any obstacles to successful implementation of your program. The following are steps that may be followed in using stakeholder analysis: INDENTFY THE STAKEHOLDERS There is need to think of all people who are to be affected by the project or strategy, those who have influence or power over it or have an interest in its successful or unsuccessful conclusion. Stake holders for Delta corporation include:-   Ã‚  Ã‚  Ã‚  Ã‚  Government departments( Zimra, RBZ, Min of industry trade and commerce, ministry of sports and culture)   Ã‚  Ã‚  Ã‚  Ã‚  Municipal authorities   Ã‚  Ã‚  Ã‚  Ã‚  Standards association   Ã‚  Ã‚  Ã‚  Ã‚  Customers   Ã‚  Ã‚  Ã‚  Ã‚  Employees   Ã‚  Ã‚  Ã‚  Ã‚  Management   Ã‚  Ã‚  Ã‚  Ã‚  Trade union   Ã‚  Ã‚  Ã‚  Ã‚  National employment council   Ã‚  Ã‚  Ã‚  Ã‚  Directors and shareholders   Ã‚  Ã‚  Ã‚  Ã‚  Suppliers   Ã‚  Ã‚  Ã‚  Ã‚  The community and the public   Ã‚  Ã‚  Ã‚  Ã‚  My family and extended family   &... ...nbsp;  Ã‚  Who else might be influenced by their opinions? Do these people become stakeholders in their own right? Talking directly to the stakeholders will help answer most of these key questions. For IT projects meeting the key stakeholders in a forum to review progress on the project is key to its success. Therefore a well drawn up project plan will ensure that there is enough representation of the stakeholders at the regular project review meetings. Identify those stakeholders that may try to bring to a halt or slowdown the successful implementation of the project. CONCLUSION In any project it is important to do a stakeholder analysis in order to be able to identify the stakeholders and prioritise them by power and their interest to the success of the strategy or project. Once you identify them there is need to fully understand what motivates them in this project and what might be done to get their much needed support, thereby reducing obstacles to successful implementation. There maybe need to dangle carrots in order to get buy in from key stake holders. Incentives and rewards goes a long way in motivating other stakeholders to get results oriented effort.